Yes! This paper really influenced me as a graduate student. Everyone should read it. Eugene Wigner wrote it. It begins with this fantastic quote from Betrand Russell:
Mathematics, rightly viewed, possesses not only truth, but supreme beauty, a beauty cold and austere, like that of sculpture, without appeal to any part of our weaker nature, without the gorgeous trappings of painting or music, yet sublimely pure, and capable of a stern perfection such as only the greatest art can show. The true spirit of delight, the exaltation, the sense of being more than Man, which is the touchstone of the highest excellence, is to be found in mathematics as surely as in poetry.
--BERTRAND RUSSELL, Study of Mathematics
The paper is an attempt to understand symmetry laws in physics and mathematics. Really, it boils down to the question of why 2+2 always equals four, and the conclusions are as deep as they come. Read this, read this, read this, here's the link to the paper.
The Unreasonable Effectiveness of Mathematics in the Natural Sciences
Also, for the economists out there, here's a paper inspired by Wigner's essay, but directed at the failings of mathematical economics.
K. V. Velupillai, The Unreasonable Ineffectiveness of Mathematics in Economics, Cambridge Journal of Economics, Vol. 29, Number 6, pp. 849--872, 2005. (Here's a .pdf of a working paper version.)
(found via the unapologetic mathematician)